Antineoplastic Bicalutamide Powder Bulk USP EP CAS: 90357-06-5
Introduction of Bicalutamide
Product Name | Bicalutamide |
Alias | Bicalutamid, ICI-176334, CASODEX |
CAS | 90357-06-5 |
MF | C18H14F4N2O4S |
MW | 430.37 |
Purity | 99.50% |
Grade | Pharmaceutical Grade |
Appearance | White Powder |
Indications | Used in the treatment of advanced prostate cancer. |
Bicalutamide is a non-steroidal androgen antagonist, which competes androgen receptor with the androgen, blocks cellular uptake of androgen, and inhibits the binding of androgens to the target organ. It binds with the androgen receptor that forms receptor complex, which enters the nucleus and combined with the nucleoprotein, consequently inhibiting tumor cell growth. It can be as a first-line drug for palliative treatment of advanced prostate cancer.
Bicalutamide is used to treat prostate cancer that has spread to other areas of the body. It is used in combination with hormone treatment. This medication works by blocking the action of male hormones in the prostate, slowing growth of the tumors.
Bicalutamide is widely metabolized in the liver. Data show that patients with severe liver damage may slow down drug clearance, which may lead to accumulation. So the patients with moderate and severe liver injury should use it with caution.
Functions of BicalutamideProstate treatment drugs, long-acting anti-androgen drugs oral non- steroidal structure,, it can be used as adjuvant treatment of advanced prostate cancer drug, may also play an important role in the treatment of early prostate cancer.
Related Antineoplastic DrugsNo. | Name | Purity | CAS |
Antineoplastic |
1 | Anastrozole | 99% | 120511-73-1 |
2 | Ansamitocin (AP3) | 99% | 69279-90-9 |
3 | Bicalutamide | 98% | 90357-06-5 |
4 | Bleomycin HCl | 98% | 67763-87-5 |
5 | Bleomycin Sulfate | 99% | 9041-93-4 |
6 | Bortezomib | 99.5% | 179324-69-7 |
7 | Cladribine | 98% | 4291-63-8 |
8 | Cytarabine HCl | 98% | 69-74-9 |
9 | Cytarabine | 99% | 147-94-4 |
10 | Dactinomycin | 99% | 50-76-0 |
11 | Dasatinib | 99% | 302962-49-8 |
12 | Daunorubicin HCl | 99% | 23541-50-6 |
13 | Doxorubicin HCl | 99% | 25316-40-9 |
14 | Epirubicin HCl | 97.5% | 56390-09-1 |
15 | Fludarabine Phosphate | 99% | 75607-67-9 |
16 | Gefitinib | 98% | 184475-35-2 |
17 | Gemcitabine HCl | 99% | 122111-03-9 |
18 | Idarubicin HCl | 98% | 57852-57-0 |
19 | Lenalidomide | 99% | 191732-72-6 |
20 | Letrozole | 99% | 112809-51-5 |
21 | Mesna | 99% | 19767-45-4 |
22 | Methotrexate | 99% | 59-05-2 |
23 | Mitomycin C | 99% | 50-07-7 |
24 | Paclitaxel | 98% | 33069-62-4 |
25 | Pentostatin | 99% | 53910-25-1 |